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PROGRAM
Program:

Program PDF file (683 KB)

  Plenary Speakers:
    PL1. Yoshinori Fujiyoshi, Japan (Kyoto University, Nagoya University)
    PL2. Florian Wurm, Switzerland (école Polytechnique Fé" dérale de Lausanne)
    PL3. Hansjörg Hauser, Germany (Helmholtz Centre for Infection Research)
    PL4. Nicole Borth, Austria (BOKU university)

    PL5. Wei-Shou Hu, USA (University of Minnesota)


  Symposia:
    S1. Biosciences on water and life
Organizers: Sanetaka Shirahara (Kyusyu University) and Gerald Pollack (University of Washington)
    Water is not only the most fundamental constituent for life, but also plays a variety of indispensable life functions.  Recently, liquid crystal water was identified.  This liquid crystal phase corresponds to the 4th phase of water, following ice, liquid, and vapor.  The liquid crystal water surrounding charged materials can store electrical and light energies, and exhibits prominent features.  Most of water in living organisms may be liquid crystal water.  Recent progress of research on the health benefit of electrochemically reduced water, which can regulate the intracellular redox mechanisms will also be discussed in this symposium.

1) The secret life of water: E = H2O)
  Gerald Pollack (University of Washington)
2)
Newest research on the health benefit of electrochemically reduced water
  Sanetaka Shirahata (Kyushu University)

    S2. Application of new cell technology for assessment of food function and safety
Organizers: Makoto Shimizu (The University of Tokyo) and Hiroaki Oda (Nagoya University)
    In food and pharmaceutical industries, many experimental animals are used to evaluate the function and safety of the product.  To reduce the number of animals, many cell culture systems have been developed, and these attempts have been successful so far.  However, many established cell lines unfortunately lose some normal functions, and it is difficult to evaluate the complex physiological responses by tissues because tissues consist of several different type of cell in vivo.  Moreover, tissue function such as intestine, liver and brain are generally expressed not from one cell type, but from the organized cell society.  To reproduce the in vivo situation in culture condition, new culture system has to be developed.  In this symposium, newly improved cell culture technology for assessment of food function and safety are presented from several experts.

1) Establishment and evaluation of biotechnological platforms for screening functional food factors
  Shu-Chen Hsieh (National Taiwan University)
2) Bioassay system for the de-methylating activity of low molecular compounds with induced pluripotent stem (iPS) cell
  Tomokazu Fukuda (Tohoku University)
3) A resealed-cell system for analyzing pathogenic intracellular events: Insight into signal transduction cascade in hyperlipidemic or diabetic cells
  Masayuki Murata and Fumi Kano (The University of Tokyo)
4) Development and application of a new genotoxicity test system with human hepatocyte cell lines
  Tsuneo Hashizume and Hiroaki Oda (Takeda Pharmaceutical Company Ltd, Nagoya University)

    S3. Cell culture technologies for stem cells
Organizers: Hiroyuki Honda (Nagoya University), Ryuji Kato (Nagoya University), and Eiji Nagamori (Osaka University)
    Recent advances in stem cell biology have provided promising results for the generation of various cell types for regenerative therapies against some of the worst diseases or novel cell diagnostic technique.  Up to date, attractive methodologies for selection of autologous adult stem cells and regulation of their differentiative direction have been established.  For their clinical or diagnostic applications, equally important is development of bioprocesses for the scalable production of stem cells.  In this symposium, cell culture technologies with new cell source, medium, methodology in the frontier of stem cell works will be presented and discussed.

1) Muse cells, a novel type of adult human pluripotent stem cells that reside in mesenchymal tissues: Their great possibility for regenerative medicine and tissue repair
  Mari Dezawa (Tohoku University)
2) A growth factor defined serum-free culture condition for human pluripotent stem cells toward the development of pharmaceutical application
  Miho K. Furue (National Institute of Biomedical Innovation)
3) The development of three-dimensional bioreactor system for pluripotent stem cell culture
  Katsuhisa Matsuura (Tokyo Women's Medical University)
4) Surface design for stem cell cultures to regulate the undifferentiated and differentiated states
  Masahiro Kino-oka (Osaka University)

    S4. Th cutting-edge technologies in single cell-based analyses and measurements
Organizers: Shun'ichi Kuroda (Nagoya University)
    Recent progress of single cell analysis have demonstrated how strongly cells can show their individually, have led us to track and catalogue this heterogeneity, and then have raised fundamental questions, "what makes individual cells different biochemically and functionally?" and "what is the role of stochastic fluctuation in the behavior of cellular molecules?"  In this symposium, the progress of recent advantages of single cell analysis and realted technologies for cell engineering will be discussed.

1) Genetically-encodable functional indicator and manipulator for deciphering biological events
  Takeharu Nagai (Osaka University)
2) Directed evolution of antibody molecules by onecell screening of yeast-displayed libraries
  Ikuo Fujii (Osaka Prefectural University)
3) Study of transport dynamics in living cell using fluorescence correlation spectroscopy
  Masataka Kinjo (Hokkaido University)
4) Automated high-throughput single cell-based breeding of biomedicine-producing cells
  Nobuo Yoshimoto and Shun'ichi Kuroda (Nagoya University)

    S5. Recent advances in CHO-omix technologies
Organizers: Hiroko Tsukamoto (Asahi Glass), Haruhiko Tsumura (Fujifilm Kyowa Kirin Biologics), Masahiko Hosobuchi (Daiichi Sankyo RD Novare), Masami Yokota (Astellas), and Takeshi Omasa (The University of Tokushima)
    The omics technologies are indispensable for understanding biological systems.  Recent developments in omics technologies have been essential for the development of rational methods of constructing a productive CHO cell line.  In this symposium, the progress of recent advances of omics analysis and related technologies for CHO cells will be discussed.

1) Chromosomal instability of Chinese hamster ovary cell
  Takeshi Omasa (The University of Tokushima)
2) Application of protein engineering for industrial production of bispecific antibody
  Tetsuya Wakabayashi (Chugai Pharmaceutical Co. Ltd.))
3) The genome sequence facilitates the improvement of protein expression system
  Yidiresi Alimujiang (Asahi Glass Co., Ltd.)

    S6. Advanced engineering in biologics production
Organizers: Hiroko Tsukamoto (Asahi Glass), Haruhiko Tsumura (Fujifilm Kyowa Kirin Biologics), Masahiko Hosobuchi (Daiichi Sankyo RD Novare), Masami Yokota (Astellas), and Takeshi Omasa (The University of Tokushima)
    Engineering approach is fundamental for industrial production of biologics.  Recently, various types of biologics are launched on the market.  Platform technologies including single-use technologies and advanced upstream and downstream processes are indispensable for rapid development of manufacturing process.  We will focus and discuss the engineering approach for platform technologies for biologics production.

1) Integrated continuous biomanufacturing platform for the production of biologics
  Tim Johnson (Genzyme)
2) Cell culture, Back to the Basics, and Beyond-Productivity enhancement and quality improvement in cell culture engineering
  Sei Murakami (Hitachi Plant Technologies, Ltd.)
3) Process development for monoclonal antibody production using design of experiments and quality by design approach
  Hiroaki Nagashima (Chugai Pharmaceutical Co. Ltd.)
4) DSM Biologics' innovative solutions to reduce costs in bioprocessing using XD fermentation and Rhobust Separation, being implemented in single use systems in the Brisbane facility (Australia) opening mid 2013
  Marc Goemans (DSM Japan KK)

 


 

JAACT2012

 

Nov. 27
(Tue)

Nov. 28
(Wed)

Nov. 29
(Thu)

Nov. 30
(Fri)

Morning

 

Plenary-1

Symposium-3

Plenary-3

Plenary-4
Symposium-5

Plenary-5 Symposium-6

Lunch Time

 

Luncheon Seminar-1

Luncheon Seminar-2

Luncheon Seminar-3

Afternoon

Opening Remarks
Murakami- Memorial

Symposium-1
Symposium-2

Plenary-2
Technical Seminar-1
Oral-presentation
Symposium-4

Technical Seminar-2
Oral-presentation
Excursion

Oral-presentation
Poster-Discussion
Closing Ceremony

Evening

Get-together Party

 

Banquet
(Tokugawaen)

 



  Banquet:

Banquet will be held at Tokugawaen.

http://www.zetton.co.jp/shop/tokugawaen/



 Excursion:
    Charted bus will bring the participants from the congress center to restaurant Tokugawa-en through each course as below. Please choose and take your favorite one.
    Admission Fee is NOT covered by registration fee. Participants are asked to pay admission fee for each facility.

    Course A: Departure 15:00 - Tokugawa Art Museum (1.5 hr trip, Admission Fee 1,000 yen)
                                              - The restaurant Tokugawa-en

    Course B: Departure 15:30 - Nagoya Castle (1 hr trip, Admission Fee 500 yen)
                                              - The restaurant Tokugawa-en

    Course C: Departure 16:45 - Direct move to the restaurant

    After the banquet, the chartered bus will arrive at "Nagoya Tokyu Hotel (Sakae)", "Sakae Station" and "Kanayama Station".

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